Here is a large part of the answer to any low adrenal/thyroid issues.

AND In the immune system the protective activity of GSH is two-fold – it enhances the activity of immune cells and also functions as an antioxidant within them.

           Need to get what is usable 

Are you:

• Low on energy?
• Lacking in mental clarity?
• Chronically ill and tired?
• Enduring a low functioning thyroid?
• Low in life force?
• Chronically fatigued?
• Have you tried everything your doctor recommends?

Perhaps it is all a matter of adjusting what is happening in your cells – naturally.

A major way to improve health and vitality and enhanced fertility is to assist the body to get back on top of all the toxins that are cascading into our bodies. Made in our own mitochondria, as natural aging, or as the deluge of chemicals have created health and fertility problems you wish help with, using the Glutathione accelerator that works will make your life so much simpler!!

An absolute must to remove all mercury and other toxic soverneirs from your having been in the wrong century with possibly the wrong parents – who themselves had more bequeathed to them than optimal.

WHAT IS GLUTATHIONE (GSH)?

Glutathione (or GSH) is the body’s own master antioxidant discovered way back in 1889. However, it was only about 30 years ago that the scientists began to understand its functions and discovered how to raise its levels. GSH is a small protein molecule composed of 3 amino acids: cysteine, glutamate, and glycine called GSH precursors or building blocks.

GSH is produced out of these three precursors in every cell of the human body and performs many important roles, such as:

• Regulation of cell growth and division
  For cells to grow and divide they go through several very complex stages. Glutathione reduces the oxides, such as hydrogen peroxide, inside the cell that would otherwise prevent cell division and growth.

• DNA synthesis and repair (synthesis – reproduction/creation of a new copy)
  Glutathione protects the DNA from oxidative stress during cell division which allows for DNA synthesis (division). When the DNA is mutated by a free radical stealing an electron from the DNA, glutathione repairs the mutated DNA by giving up an electron to the DNA (replacing the DNA’s missing electron).

• Protein synthesis
  Glutathione maintains our proteins in their proper form. Its sulfur atom reacts with unnatural sulfur-sulfur bonds in proteins, breaking them and allowing the proper pairings to form.

• Amino acid transport
  (Transport – movement into, out of, within a cell, or between cells, by means of some agent such as a transporter)
  Glutathione is predominately located in the cell, whereas a major fraction of the cellular y-glutamyl transpeptidase (glutathione enzyme) is on the external surface of cell membranes. This means intracellular glutathione is translocated out of many cells – glutathione moves substances, such as amino acids, in and out of the cel

• Enzyme catalysis
  Glutathione provides the mechanism by which many enzymes are changed (reduced, transformed or changed from one state to another state). Glutathione is the bridge (catalysis) in the chemical reaction between some enzymes.

• Enzyme activation
  The highly reactive sulfide bond in glutathione wakes up or activates enzymes so that they carry out their function or are moved from one phase to the next.

• Metabolism of toxins (metabolism or biotransformation – breaking down, activating or transforming)
  In the liver, the enzyme glutathione S-transferase takes the sulfur from glutathione and attaches it to toxic molecules, this makes the toxin more water soluble (it is diluted in water easily). Once a toxin is water soluble, it is transported to the body’s elimination systems and is excreted from the body.

• Metabolism of carcinogens
  Glutathione enzymes transform carcinogens, through chemical reaction, to unreactive and non-genotoxic compounds that can be eliminated without causing damage to the cell or DNA.

• Metabolism of xenobiotics (xenobiotics – chemical components (drugs and poisons) foreign to the body)
  Glutathione interacts with foreign chemicals (primarily, it is a scavenger of harmful xenobiotics that have been oxidized) compounds to neutralize and break them down, then eliminate them from the body.

• Conjugation to heavy metals (conjugation – joining with and transforming by becoming part of)
  Glutathione joins with heavy metals to neutralize them and eliminate them from the body.

• Conjugation to xenobiotics
  In some instances, depending on the state of the xenobiotic, glutathione joins with it instead of metabolizing it.

• Enhancement of systemic immune function
  The immune system works best if the lymphoid cells have properly balanced glutathione. The cloning of T-cells consumes large quantities of cysteine. Macrophages (type of white blood cells), which are only present in sufficient quintiles when there is sufficient glutathione, provide the cysteine for the T-cell cloning. Glutathione regulates the binding, internalization, degradation and T-cell proliferation by increasing, as much as two times, the number of binding cellular receptors. More receptors equates to more T-cells being produced simultaneously (multiple T-cell cloning). Cellular GSH also affects the growth and replication of T-cells through growth stimulating cytokines.

• Enhancement of humoral immune function
  The role of glutathione in the humoral response is that it protects the cells taking part in the humoral response all along this complex process.
  A quick synapsis of the humoral immune response: “humoral” means circulating in the bloodstream. This is an immune response (chiefly against bacterial invasion) that is mediated by B cells and involves the transformation of B cells into plasma cells that produce and secrete antibodies to a specific antigen.
  The process in a nutshell: macrophages engulf and digest the invading pathogen. The digested pieces activate helper T cells which in turn activate the proliferation of B cells that are programed for the specific invading pathogen

• Resistance to UV radiation
  Glutathione detoxifies reactive oxygen radicals created by radiation which reduces the damage to the cell. Glutathione also interacts covalently and noncovalently (neutralizes the reactivity in several ways) with parts of the cell that keep the cell from triggering apoptosis (cell death).

• Decreases radiation damage
  The action of glutathione in decreasing the damage from radiation is the same as in resistance to UV radiation above.

• Decreases free radical damage
  The crucial cysteine molecule is the key to the protection afforded by glutathione. Its sulfur atom scavenges destructive molecules (peroxides and free radicals) converting them to harmless compounds, such as water.

• Decreases oxyradical damage
  Glutathione detoxifies reactive oxygen radicals by giving them an electron which effectively neutralizes them, or glutathione joins with the oxyradical which again neutralizes it.

• Metabolizing of hydrogen peroxide (H2O2)
  Glutathione biotransforms hydrogen peroxide by turning it into harmless water.

• Recycling of other antioxidants (master antioxidant role)
  Glutathione recycles oxidized lipoic acid, vitamin C and E by restoring them to an active state, mostly by donating the electrons that they used in metabolizing (neutralizing) free radicals. So, instead of having this army of antioxidants flushed out, they are recycled by glutathione and sent back out to work.

• Storage and transport of cysteine
  Glutathione is a tripeptide made up of amino acids CYSTEINE, glycine and glutamate. Glutathione provides and determines the amount and availability of neuronal cysteine.

• Regulation of homocysteine
  The methionine cycle and the transsulfuration sequence compose the mechanisms for homocysteine metabolism. Transsulfuration sequence requires large quantities of cysteine. It is suspected that the rapid turnover of glutathione in the liver, kidneys, small intestine and pancreas accounts for the metabolism of homocysteine in these organs. Homocysteine metabolism also involves multiple enzymes. Excessive homocysteine is a known contributing factor of hardening of arteries (atherosclerosis).

Jean Carper in her book “Stop Aging Now!” claims: “You must get your levels of GSH up if you want to keep your youth and live longer. High levels of GSH predict good health and long life. Low levels predict early disease and death.”

WHY IS GLUTATHIONE IMPORTANT?

The immune system and detoxification system cannot function without GSH. In his book “Glutathione. Your body’s most powerful protector” Dr. Jimmy Gutman says “Glutathione modulation is an essential part of staying young, active and healthy.” He also states – “By keeping our intracellular GSH levels up we also keep our immune system on the ball and fully armed”.

GSH has been clinically researched and proven to optimize your immune system, maximize the function of antioxidants, support your detoxification process at the cellular level, increase your energy levels and increase your strength and endurance.

As of April 2012, Pubmed.gov (the government’s depository for research articles in medical and biomedical fields) lists 100,775 medical articles mentioning GSH. This is a tremendous amount of research and energy that the medical profession has put into understanding the role of GSH in our lives. Optimizing your GSH levels benefits everyone, from children to those in their golden years, from the infirm to the elite athlete.

To be more specific about the articles I have researched to date, raising GSH level has been CLINICALLY PROVEN to be beneficial for people afflicted with: AIDS, Alzheimer’s, asthma, burns, all CANCERS, cataracts, chronic fatigue syndrome, diabetes, autoimmune disorders, diseases of liver, kidneys, lungs, heart, and digestive system, flu, fibromyalgia, glaucoma (open angle only, closed angle not effected), hepatitis, multiple sclerosis, Parkinson’s, physical trauma, skin disorders, seizures, tumors, and more. To state something is beneficial to your health is one thing but to prove it clinically is to give it validity.

Do not under appreciate the profound meaning of this statement – raising your GSH level is CLINICALLY PROVEN TO BE BENEFICIAL for a very wide array of health concerns. The research continues at an amazing pace. If you want to know what research has been done for your particular condition go to PubMed and simply type in your condition. It will list the abstracts of related articles. If you want to know what influence GSH plays in your condition, type in “glutathione and your condition”, then hit Search. I was amazed at what has been researched and is not common knowledge.

Glutathione Deficiency

Glutathione deficiency occurs when your body is unable to produce enough glutathione to cover all the functions which this master antioxidant performs. Decreased glutathione levels are usually the result of a lifestyle that is characterized by the many factors that deplete glutathione.

Glutathione deficiency leads to:

• increased oxidative stress
• greatly reduced ability to detoxify
• accumulation of toxins and heavy metals
• inability to repair DNA
• cell mutations
• weakened cell membranes
• reduced supply of oxygen and nutrients to the cells
• eventual cell death

These processes directly affect the state of the immune system and often become the main cause of the onset of the disease, or its progression, severity, and response (or, rather, the lack of it) to treatments.

Low glutathione also means that the prescribed treatments, instead of helping, may actually aggravate the condition since drugs cause further decline in glutathione levels. For example, it has been documented scientifically that glutathione levels can predict how long HIV patients are able to survive, or how well and with what side effects cancer patients can tolerate chemotherapy and radiation.

Research has shown that almost all chronic conditions are characterized by glutathione deficiency: HIV/AIDS, Alzheimer’s, asthma, all cancers, cataracts, macular degeneration, glaucoma (open angle only), chronic fatigue syndrome, diabetes, autoimmune disorders, all diseases of liver, kidneys, lungs, heart, and digestive system, fibromyalgia, flu and colds, peripheral neuropathy, hepatitis, multiple sclerosis, Parkinson’s, skin disorders, seizures, tumors, autism spectrum disorders and more, as well as non-chronic conditions, such as burns, physical trauma and any type of surgery.

Only people with serious chronic conditions and those undergoing harsh treatments are severely deficient in glutathione. They respond quickly and positively to even minimal increases in glutathione levels.

In peripheral neuropathy, decades of Standard American Diet (SAD), high levels of prolonged stress and possible exposure to toxins during his professional career as a field engineer caused glutathione deficiency that led to the onset and rapid progression of the disease. When he started his glutathione boosting regimen he saw a considerable improvement within several days and an 80-90% reduction in pain levels and pain area after 4-6 weeks of his regimen (described at the bottom of the Peripheral Neuropathy page).

People who consider themselves to be in good health may not necessarily be glutathione deficient but may still have declining glutathione levels. The main reason for that is age first of all, because glutathione production in cells declines naturally at an average rate of 10% per decade after age 20. Secondly, on a daily basis we all are exposed to environmental pollution, exhaust fumes, smoke, viruses and do not always eat nutritious homemade meals with recommended 7-9 servings of organic vegetables and fruit a day.

Such a lifestyle eventually leads to a certain degree of glutathione deficiency.

The symptoms may include: (all chronic ‘illnesses’ – eg long range . . .. . )

• headaches
• dizziness
• weakness/lack of energy
• brain “fog”
• joint pain
• rashes
• dry skin
• sleep disorders
• depression
• frequent colds
• onset of a more serious health condition

Healthy people may not notice instantaneous results when boosting glutathione levels. However, they will notice improvement in energy levels, mind clarity, improved sleep and mood, and will see fewer colds. Those who do power workouts several times a week will see faster recovery times, reduced muscle soreness and improved athletic performance (The Effect Of Supplementation With A Cysteine Donor On Muscular Performance. Lands LC, J Appl Physiol.Oct;87(4) :1381-5 (1999).

Glutathione deficiency can be brought on by gene mutations or missing genes GSTT1, GSTM1, GSTM2, GSTP1, MTHFR C677T homozygous and others. These genes regulate the production and activity of glutathione enzymes and affect metabolism of cysteine, folate and B vitamins – these enzymes and glutathione cofactors regulate how much glutathione the body is able to produce.

If glutathione deficiency is so detrimental to our health and longevity how do we raise and maintain optimal levels of this crucial master antioxidant? There are at least 19 options of how to raise glutathione that I was able to find and research. Only a few of them have had trials proving scientifically that they raise glutathione in humans.

WHAT DEPLETES GLUTATHIONE in our bodies? (Modern life)

       What depletes glutathione (GSH) levels in our bodies can be put into two categories – internal and external factors.

Internal factors include the increasing need for glutathione as an important part of various processes in our bodies, such as, food for our immune system, recycling of vitamin C, vitamin E and alpha lipoic acid, repairing our DNA, and protecting our cells from oxidative stress to mention a few.

Many external factors is what depletes glutathione the most.

Many toxic and harmful substances that we are exposed to on a daily basis require considerable amounts of glutathione for detoxification.

Some of these substances are listed here

• acetaminophen (Tylenol) and other pharmaceuticals;
• acetone, solvents, paint removers;
• fuels and fuel by-products;
• heavy metals (mercury (dental amalgams, vaccines, tattoos), lead, cadmium, copper, etc.);
• pesticides, herbicides;
• nitrates and other food preservatives of chemical origin (in salami, hot dogs, hams, bologna, smoked foods, etc.);
• artificial sweetener aspartame;
• synthetic food dyes;
• benzopyrenes (tobacco smoke, barbequed foods, fuel exhaust, etc.);
• alcohol;
• household chemicals (synthetically scented and colored detergents and fabric softeners, air fresheners, mothballs, mildew removers, cleaners and bleach, lawn and plant fertilizers, etc.);
• housewares chemicals (non-stick coating of pans and skillets, plastic containers and linings of tin cans and other food packaging);
• formaldehyde and styrene (photocopiers and toner printers);
• chlorine in treated water;
• medical X-rays;
• UV radiation;
• electromagnetic fields (EMF);
• industrial pollutants.

Other external factors that deplete glutathione:

• poor diet – in this case glutathione has to work hard to cover for missing or insufficient antioxidants, and the lack of glutathione cofactor vitamins and minerals impairs glutathione synthesis and proper functioning;
• strenuous exercise – though not a toxic substance but produces a lot of free radicals within the body;
• chronic stress;
• anxiety;
• depression;
• light pollution which lowers glutathione levels by suppressing melatonin production at night (bedside night lights, street lights);
• age – after the age of 20 natural glutathione production decreases at the rate of 10% per decade on average in healthy adults.

This list of what depletes glutathione in your body, though incomplete, is quite remarkable

We cannot completely avoid all of these substances. But we can minimize our exposure in most instances by making simple changes to our daily habits. There are two ways to do that:

1. To strive to reduce exposure to as many of the above toxins as possible. For tips on what simple changes you could make in your daily life visit our page Ways to Boost Your Immune System.

2. To raise glutathione to its optimum levels in order to maintain an adequate immune response. To learn about most known ways to raise your glutathione levels and their pros and cons visit our page How To Raise Glutathione.

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WHAT DOES GLUTATHIONE DO IN OUR BODIES?

Antioxidant – GSH is the body’s master Antioxidant, our bodies depend on GSH for the removal of toxins and GSH is at the heart of all immune functions. Other antioxidants in our body depend on GSH to function properly.

Detoxification – GSH detoxifies a large number of pollutants by binding to carcinogens, heavy metals, herbicides, pesticides and radiation by forming a soluble compound with the toxin that can then be excreted through the urine or bile.

Immune system – Healthy growth and activity of immune cells depends on the availability of GSH. The protective activity of GSH is two-fold – it enhances the activity of immune cells and also functions as an antioxidant within them.

Increased Energy – Our energy levels are a result of many factors – everything from the biochemical reactions taking place within our cells, to muscle function and even your sense of well-being. GSH enables the mitochondria of a cell to remain fully charged, enhancing muscle strength and endurance. Clinical trials have shown that lowering GSH in the mitochondria results in cell death.

Repair – Our body is constantly under attack from free radicals, some from external sources and some generated in our own body. Free radicals attack the nearest stable molecule, “stealing” its electron. A molecule that loses an electron then becomes a free radical itself and attacks the next nearest stable molecule, this begins a chain reaction. Once the reaction is started it can cascade through hundreds of molecules. As this occurs over and over again the cell eventually dies or mutates. Sometimes the mutated cell mutates to a point that we know as cancer. GSH performs a vital role in repairing the damaged DNA by replacing the missing electron. Normal to elevated GSH keeps the repair of our cells at a maximum and reduces the number of cell mutations that would occur otherwise.

GSH is at the heart of all immune functions and low GSH levels are seen in many diseases such as AIDS, advanced diabetes, and cancers. Raising and maintaining GSH levels can help minimize the risk of diseases.

Glutathione exists in reduced (GSH) and oxidized (GSSG) states. In healthy cells and tissue, more than 90% of the total Glutathione is in the reduced form (GSH) and less than 10% exists in the oxidized form (GSSG). An increased GSSG-to-GSH ratio is considered indicative of oxidative stress. The ratio of reduced Glutathione to oxidized Glutathione within cells is often used scientifically as a measure of cellular toxicity.

A capsule saying Glutathione  will be about 1% available as your body breaks it down
WHEREAS – taking 6 of these capsules daily with food – at breakfast – will massively change your life.

Glutathione – the Master Anti-Oxidant – MUST use orally as the accelerator

People With Higher Glutathione Levels:

• Have More Energy
• Recover Faster From Exercise
• Sleep Better
• Have Greater Mental Clarity and Focus
• Less Inflammation
• Improved Joint Function
• Have Better Immune Systems
• Live Longer
• Live Better
• Improve the Health and Function of Every Cell, Tissue and Organ in the Body

Glutathione is a substance that is found in every cell of the body, and has been called the master antioxidant. It is such an important antioxidant as it is actually within the body’s cells and it also regulates the actions of lesser antioxidants such as vitamin C and vitamin E.

Glutathione is made in our body for mitochondrial repair, is life’s ultimate anti oxidant and major ‘anti rust’/anti inflammatory agent. You, like me till a few years ago, may have not have heard of this. Glutathione is not easily made as a supplement. We produce it in our cells in the mitochondria.  It breaks down in the stomach when the ingredients are not all presented at exactly the right dosages as a pill – hence it is not able to be sold as is unless through the patented version that Dr Robert Keller discovered. Usual oral versions are broken down. Esp in all cases of fertility issues.

It is essential for all life. What to do? Besides pepping yourself up instantly and renewing your health effectively through taking this as an amazing supplement.

Perhaps eat more varied and simple, natural diet.

Sulphurous foods, and massive amounts of fresh dark green leafy veggies.

Ingredients for this often missing in modern diet

‘Why haven’t I heard of this before?’ you may ask.

I had been a naturopath and an acupuncturist for over 30 years – and I hadn’t either.

Why do we not hear more of the most basic antioxidant in every cell in the body, without which we radically age?

Without an ample supply of Glutathione we have inflammation and accelerated aging – lowering the quality of all life – especially in the reproductive area when the embryos just don’t make it. Think QUALITY – what are we making and with what?

Natural life does not need as many antioxidants as the life you are probably living – lack of regenerative sleep (and not enough of it), poor hydration, nutrition and very little ‘down time’ to enjoy being alive.

Glutathione is the most important antioxidant in the body and is vital for health, but what exactly does it do?

A walk through my natural healing practice . .

What is Glutathione?

Glutathione is a tri-peptide that is made up of gamma-glutamic acid, cysteine, and glycine, and is also known as gamma-glutamylcysteinelglycine or GSH.

Glutathione is a substance that is found in every cell of the body, and has been called the master antioxidant. It is such an important antioxidant as it is actually within the body’s cells and it also regulates the actions of lesser antioxidants such as vitamin C and vitamin E.

If the levels of glutathione are too low in the body, other antioxidants are unable to do their job.

Glutathione is the regulator and regenerator of immune cells. It is important in DNA synthesis and repair, protein and prostaglandin synthesis, amino acid transport, detoxification of toxins and carcinogens, enhancement of the immune system, and protection from oxidation and enzyme activations.

Glutathione has strong antiviral properties. If there are higher levels of glutathione in the tissues and serum, then the replication of most pathogens are stopped. Conversely, if the levels of glutathione are low, then conditions become much more favourable for viruses.

Glutathione may not be well absorbed into the body when taken by mouth. However, it is more practical to take the precursors to glutathione – the substances that the body needs to make glutathione.

How to Boost Your Glutathione Levels

Supplements containing the building blocks that our bodies need to create our own glutathione are now available!

Dr Robert H Keller was the originator of this incredible formula. The Original Glutathione Formula (OGF) is the most outstanding Glutathione precursor on the market today.

Robert H. Keller, MD, MS, FACP, AAHIVS

Dr Keller had a distinguished academic career after achieving MD with Honors, and being elected to AOA at Temple University, and training in Internal Medicine, Immunology and Hematology at the University of Rochester and the Mayo Clinic.

The Consumer’s Research Council named him one of America’s Top Physicians in 2003, 2004, 2005, 2006, 2007, and 2008 in the fields of Internal Medicine, Immunology and Hematology.

Around 1996, Dr. Keller began working on a supplement to raise one’s intracellular glutathione levels. His many years of trial and error led to a great success as in 2006 he introduced his glutathione boosting supplement to the market.

This is such a powerful product it has been given a compositional patent normally reserved for pharmaceutical drugs.

It is now marketed under the name Rob Keller MD Original Glutathione Formula.

Dr. Keller worked for 10 years formulating the product. He would often joke that it was “10 years of perspiration and 1 minute of inspiration”.

Listen to Dr Keller talking about how to live better again

And here . .
This is a little bit technical . .
Please listen – as when you have no hope/concerns as the G.P.’s and all others seem to NOT pay attention to aging well . . .

Let alone being unwell as a younger person . .
I also knew NOTHING about this – and that is a a natural health care professional – until someone mentioned it – and ye s- I have been on this ever since – not taking other supplements – ALWAYS this – as taking 6 of these a morning (with food) I do not need to take other things – and my thyroid works!!!

Get yours here

Click the audio link below to hear Dr Keller:

The discount is only good for:

• New Customers
• One product in your first order (you will not get discounts on all the products if you order more than one)
• First month for a subscription order (you will be charged the regular price after your first month)